Prostate cancer is one of the most common types of cancer in men and one of the leading causes of cancer death across the globe. Common prostate screening procedures include rectal examination, prostate-specific antigen (PSA) testing and ultrasound imaging. Nevertheless, prostate cancer can only be properly confirmed from a biopsy of the prostate tissue. This involves acquiring a number of small tissue samples from the patient and grading them according to the Gleason grading system:

In some cases, the tissues collected for biopsy may not include the tumor, leading to a false negative diagnosis. A current project from our group involves the analysis of a dataset containing whole-mount prostate histology images of 10 specimens having different stages of prostate cancer. We aim at proposing new methodologies for detecting tissue features associated with prostate cancer, as well as to identify the likelihood that a biopsy can lead to a wrong Gleason grading given the number and size of collected samples.